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Thursday, 08 October 2009 13:02
Maintenance Chemotherapy for Cancer Survivors?
Written by Dr. Susan Hardwicke
At first blush, the news sounds at worst neutral: more life-saving chemotherapy can be administered to increase longevity. " But, for cancer survivors who have experienced chemotherapy, it means that their remaining years are characterized by increased debilitation and low quality of life.
At the recent annual meeting of the American Society of Clinical Oncology," doctors filled a huge auditorium for a debate on whether it is time to adopt maintenance therapy for lung cancer, the nation’s leading cause of cancer death. Other cancers for which maintenance therapy is being used or tried include ovarian cancer, multiple myeloma and non-Hodgkin’s…
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Thursday, 05 November 2009 17:37
Breast Cancer Awareness Month: Startling Realizations at the Crossroads of Pink
Written by Jesse Stretch
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The strange and outright tragic truth behind the ulterior motives for the creation and continuance of Breast Cancer Awareness Month are both startling and eye-opening. On one hand, a cancer survivor may feel cheated or threatened, but at the same time there is a call to action when confronted with the fact that, for many pharmaceutical and chemical manufacturing companies, BCAM is merely another notch on the…
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Are Fertility Drugs a Cancer Risk?
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Fertility medications appear to increase the development of uterine cancer, as well as some other forms of disease. Drugs used to stimulate ovulation have been used for quite some time to help women conceive children, but the drugs’ impact on the overall health of patients has never been clarified.
Original studies conducted in response to this issue were inconclusive and led to few, if any, concrete findings. Whether these medicines actually contributed to a rise in ovarian or breast cancer has been hidden since these medicines came into existence many years ago.
The…
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Tuesday, 20 October 2009 15:56
Your body may have a built-in "danger receptor" for alerting the immune system
Written by Jesse Stretch
In the closing stages of a hunt that has lasted over 15 years, researchers at the London Research Institute in Great Britain believe they have finally located the well-hidden cell "danger receptor." The danger receptor, found on certain specialized cells within the human body, is capable of sensing cell death, abnormalities, or malignant tissue, and signaling the mobilization of the boy’s immune system.
These findings may shed light on the previously unknown workings of several cancer-fighting drugs that simulate the signaling of these receptors, thereby causing the immune system to respond and act against certain intruding cells. The researchers believe…
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Tuesday, 03 November 2009 16:41
Prostate Cancer - Insulin a factor in disease progression?
Written by Jesse Stretch
Prostate Cancer - New Information from the National Cancer Institute
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Recent findings concerning prostate cancer were published in the Journal of the National Cancer Institute. A lengthy direct quote from the source has been included below as a means of relating this information as straightforwardly as possible.
The NCI research stated that, "The mitogenic and growth-stimulatory effects of insulin-like growth factors appear to play a role in prostate carcinogenesis, yet any direct association of circulating insulin levels and risk of prostate cancer remains unclear. We investigated the relationship of the level of serum insulin, glucose, and surrogate indices of…
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Monday, 26 October 2009 18:34
Advancement in Cancer Detection: The Discovery of the Natural Killer Cell
Written by Editor
In 1972, Jerry T. Thornthwaite presented a poster session with Professor, Dr. Bob Leif, at the annual Reticuloendothelial Society Meeting. The poster presented very unusual cells from the spleen (and later from the lymph nodes) of non-immunized mice that destroyed sheep red blood cells (SRBC) on contact. Thornthwaite came close to publishing the article in Science, but the conclusion proved it was more suitable for immunology journals and was later accepted.
Defining the name of these cells was a challenge, but he was able to develop a way of enumerating them, determining density and enrichment in the linear bovine serum…
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Tuesday, 21 April 2009 21:15
New Imaging Analysis Predicts Brain Tumor Survival
Written by University of Michigan
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Ann Arbor, MI - As early as one week after beginning treatment for" brain tumors, a new imaging analysis method was able to predict which patients would live longer, researchers from the University of Michigan Comprehensive Cancer Center have found.
Scans showing gliomas that did not (left) and did (right) respond to treatment. Top images are parametric response maps superimposed onto pre-treatment MRIs. Graphs show distribution of relative cerebral blood volume for entire tumor volume." Meet the ExpertsBrian Ross, Ph.D.Craig Galbán, Ph.D.Read the ReportDownload the images
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The method uses a standard" magnetic resonance imaging, or MRI, protocol to monitor changes over…
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Sunday, 19 April 2009 21:10
National Cancer Institute's Plan to Accelerate Cancer Research Announced
Written by National Cancer Institute
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At the American Association for Cancer Research 100th Annual Meeting 2009 in Denver, National Cancer Institute (NCI) Director John E. Niederhuber, M.D., announced major details, such as funding more grants, development of a platform for personalized cancer care, and an accelerated cancer genetics program, that will move cancer research forward in this new economic environment. NCI is part of the National Institutes of Health (NIH).
"We must hasten our progress against cancer by conducting exciting new science, which this year's increase in funding, in addition to anticipated funds from the American Recovery and Reinvestment Act, will help make possible,"…
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Sunday, 19 April 2009 21:07
Researchers Discover Potential Functional Role of Genetic Variation in Prostate Cancer Risk
Written by National Cancer Institute
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Researchers have described how a common genetic variation may be involved in the development of prostate cancer. The variant occurs in a gene known to be involved in prostate function. The study, which included a team of researchers at the National Cancer Institute (NCI), part of the National Institutes of Health, uncovered how a small change in the DNA of the gene impacts the biology of prostate cancer risk. The study was published online April 20, 2009, in Proceedings of the National Academy of Sciences.
Differences in the sequence of DNA among individuals are called genetic variations, and some…
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Tuesday, 21 April 2009 21:05
U.S. Cancer Screening Trial Shows No Early Mortality Benefit from Annual Prostate Cancer Screening
Written by National Institutes of Health
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Six annual screenings for prostate cancer led to more diagnoses of the disease, but no fewer prostate cancer deaths, according to a major new report from the Prostate, Lung, Colorectal, and Ovarian (PLCO) Cancer Screening Trial, a 17-year project of the National Cancer Institute (NCI), part of the National Institutes of Health. The PLCO was designed to provide answers about the effectiveness of prostate cancer screening.
"What this report tells us is that there may be some men who are diagnosed with prostate cancer and have the side-effects of treatment, such as impotence and incontinence, with little chance of…
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Tuesday, 05 May 2009 21:04
Enzon Reveals New LNA Targets -- Data presented at American Associa
Written by Editor
Enzon Reveals New LNA Targets--" Data will be presented at upcoming American Association for Cancer Research Meeting--
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BRIDGEWATER, NJ – March 19, 2009 – Enzon Pharmaceuticals, Inc. (Nasdaq: ENZN) today announced new novel Locked Nucleic Acid (LNA) programs directed against, the Androgen receptor (AR) and Phosphoinositide 3-kinase (PI3K/Akt)." These targets are linked to a broad spectrum of cancers." Enzon has licensed eight novel LNA targets from Santaris Pharma A/S.
The abstracts related to these new targets and other Enzon programs are now available at" www.aacr.org." These data will be presented at the upcoming 2009 Annual Meeting of the American Association for…
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Thursday, 30 April 2009 20:59
Researchers Discover Potential Functional Role of Genetic Variation in Prostate Cancer Risk
Written by National Cancer Institute
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Researchers have described how a common genetic variation may be involved in the development of prostate cancer. The variant occurs in a gene known to be involved in prostate function. The study, which included a team of researchers at the National Cancer Institute (NCI), part of the National Institutes of Health, uncovered how a small change in the DNA of the gene impacts the biology of prostate cancer risk. The study was published online April 20, 2009, in Proceedings of the National Academy of Sciences.
Differences in the sequence of DNA among individuals are called genetic variations, and some…
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DENVER - Meat cooked at high temperatures to the point of burning and charring may increase the risk of pancreatic cancer, according to data presented at the American Association for Cancer Research 100th Annual Meeting 2009.
Kristin Anderson, Ph.D., associate professor at the University of Minnesota School of Public Health, said the finding was linked to consumption of well and very well done meats cooked by frying, grilling or barbecuing. Cooking in this way can form carcinogens, which do not form when meat is baked or stewed.
Anderson and colleagues conducted a prospective analysis that included 62,581 participants. "My…
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Wednesday, 06 May 2009 19:36
Drinking Wine May Increase Survival among Non-Hodgkin’s Lymphoma Patients
Written by AACR
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DENVER - Pre-diagnostic wine consumption may reduce the risk of death and relapse among non-Hodgkin's lymphoma patients, according to an epidemiology study presented at the American Association for Cancer Research 100th Annual Meeting 2009.
Xuesong Han, the first author of the abstract and a doctoral candidate at the Yale School of Public Health, said their findings would need to be replicated before any public health recommendations are made, but the evidence is becoming clearer that moderate consumption of wine has numerous benefits.
"This conclusion is controversial, because excessive drinking has a negative social and health impact, and it is…
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